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The HH signaling inhibitor GANT61 has an impact on HH target gene... |  Download Scientific Diagram
The HH signaling inhibitor GANT61 has an impact on HH target gene... | Download Scientific Diagram

Targeting the hedgehog signal transduction pathway at the level of GLI  inhibits neuroblastoma cell growth <i>in vitro</
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth <i>in vitro</

GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide  treatment | Journal of Experimental & Clinical Cancer Research | Full Text
GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment | Journal of Experimental & Clinical Cancer Research | Full Text

Frontiers | The Combination of Particle Irradiation With the Hedgehog  Inhibitor GANT61 Differently Modulates the Radiosensitivity and Migration  of Cancer Cells Compared to X-Ray Irradiation | Oncology
Frontiers | The Combination of Particle Irradiation With the Hedgehog Inhibitor GANT61 Differently Modulates the Radiosensitivity and Migration of Cancer Cells Compared to X-Ray Irradiation | Oncology

Cells | Free Full-Text | Recent Advances in the Clinical Targeting of  Hedgehog/GLI Signaling in Cancer | HTML
Cells | Free Full-Text | Recent Advances in the Clinical Targeting of Hedgehog/GLI Signaling in Cancer | HTML

GANT 61 Supplier | CAS 500579-04-4 | GANT61 | Tocris Bioscience
GANT 61 Supplier | CAS 500579-04-4 | GANT61 | Tocris Bioscience

Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression  and Inhibits Proliferation of Canine Osteosarcoma Cells
Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression and Inhibits Proliferation of Canine Osteosarcoma Cells

Reproducibility of academic preclinical translational research: lessons  from the development of Hedgehog pathway inhibitors to treat cancer | Open  Biology
Reproducibility of academic preclinical translational research: lessons from the development of Hedgehog pathway inhibitors to treat cancer | Open Biology

Scheme 1. Synthetic pathway to obtain both GANT61-D and GANT61. | Download  Scientific Diagram
Scheme 1. Synthetic pathway to obtain both GANT61-D and GANT61. | Download Scientific Diagram

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine  derivatives inhibits melanoma cell growth by inducing replication stress  and mitotic catastrophe | Cell Death & Disease
Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe | Cell Death & Disease

GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide  treatment | Journal of Experimental & Clinical Cancer Research | Full Text
GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment | Journal of Experimental & Clinical Cancer Research | Full Text

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

GANT61 | ≥99%(HPLC) | Selleck | Hedgehog/Smoothened inhibitor
GANT61 | ≥99%(HPLC) | Selleck | Hedgehog/Smoothened inhibitor

The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer? -  Abstract - Europe PMC
The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer? - Abstract - Europe PMC

GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide  treatment | Journal of Experimental & Clinical Cancer Research | Full Text
GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment | Journal of Experimental & Clinical Cancer Research | Full Text

Targeting the hedgehog signal transduction pathway at the level of GLI  inhibits neuroblastoma cell growth in vitro and in vivo - Wickström - 2013  - International Journal of Cancer - Wiley Online Library
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo - Wickström - 2013 - International Journal of Cancer - Wiley Online Library

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

GANT 61 (NSC 136476) | Gli1/2 Inhibitor | MedChemExpress
GANT 61 (NSC 136476) | Gli1/2 Inhibitor | MedChemExpress

Table 23.1 from Hedgehog inhibition as an anti-cancer strategy. | Semantic  Scholar
Table 23.1 from Hedgehog inhibition as an anti-cancer strategy. | Semantic Scholar

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

GANT-61 treatment to RMS cells inhibits proliferation, colony formation...  | Download Scientific Diagram
GANT-61 treatment to RMS cells inhibits proliferation, colony formation... | Download Scientific Diagram

Effect of GANT61 and IR in vivo. (A) Relative tumor growth of 22Rv1... |  Download Scientific Diagram
Effect of GANT61 and IR in vivo. (A) Relative tumor growth of 22Rv1... | Download Scientific Diagram

GANT61 inhibits the expression of GLI1, GLI2 and Bcl-2. a GANT61... |  Download Scientific Diagram
GANT61 inhibits the expression of GLI1, GLI2 and Bcl-2. a GANT61... | Download Scientific Diagram

Chemical, computational and functional insights into the chemical stability  of the Hedgehog pathway inhibitor GANT61
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via  JNK-dependent but p53-independent mechanism - ScienceDirect
RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism - ScienceDirect

The role of hedgehog signaling in gastric cancer: molecular mechanisms,  clinical potential, and perspective. - Abstract - Europe PMC
The role of hedgehog signaling in gastric cancer: molecular mechanisms, clinical potential, and perspective. - Abstract - Europe PMC