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Edice Oslabit Alabama overall mutation load and p53 mutations Ztělesňovat rozšířit Notoricky známý

Therapeutic targeting of p53: all mutants are equal, but some mutants are  more equal than others | Nature Reviews Clinical Oncology
Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others | Nature Reviews Clinical Oncology

Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell  Lymphoma | NEJM
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM

TP53 Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck  | NEJM
TP53 Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck | NEJM

Comprehensive Analysis of TP53 and KEAP1 Mutations and Their Impact on  Survival in Localized- and Advanced-Stage NSCLC - Journal of Thoracic  Oncology
Comprehensive Analysis of TP53 and KEAP1 Mutations and Their Impact on Survival in Localized- and Advanced-Stage NSCLC - Journal of Thoracic Oncology

Mutations in exon 8 of TP53 are associated with shorter survival in  patients with advanced lung cancer
Mutations in exon 8 of TP53 are associated with shorter survival in patients with advanced lung cancer

MPs | Free Full-Text | Characterising Mutational Spectra of Carcinogens in  the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse  Embryo Fibroblasts | HTML
MPs | Free Full-Text | Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts | HTML

Frontiers | Mutant p53 Gain-of-Function: Role in Cancer Development,  Progression, and Therapeutic Approaches
Frontiers | Mutant p53 Gain-of-Function: Role in Cancer Development, Progression, and Therapeutic Approaches

Parainflammation is associated with p53 mutations. a Percentage of p53... |  Download Scientific Diagram
Parainflammation is associated with p53 mutations. a Percentage of p53... | Download Scientific Diagram

Specific TP53 subtype as biomarker for immune checkpoint inhibitors in lung  adenocarcinoma - ScienceDirect
Specific TP53 subtype as biomarker for immune checkpoint inhibitors in lung adenocarcinoma - ScienceDirect

Significance of TP53 mutation in bladder cancer disease progression and  drug selection [PeerJ]
Significance of TP53 mutation in bladder cancer disease progression and drug selection [PeerJ]

P53 mutations in cancer and aggregation segments. Tumor site... | Download  Scientific Diagram
P53 mutations in cancer and aggregation segments. Tumor site... | Download Scientific Diagram

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene

Correlation of TP53 mutations with HCV positivity in hepatocarcinogenesis:  Identification of a novel TP53 microindel in hepatocellular carcinoma with  HCV infection
Correlation of TP53 mutations with HCV positivity in hepatocarcinogenesis: Identification of a novel TP53 microindel in hepatocellular carcinoma with HCV infection

Cancers | Free Full-Text | TP53 Mutations as a Driver of Metastasis  Signaling in Advanced Cancer Patients | HTML
Cancers | Free Full-Text | TP53 Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients | HTML

Location, frequency, and type of TP53 mutations in ALL. The locations... |  Download Scientific Diagram
Location, frequency, and type of TP53 mutations in ALL. The locations... | Download Scientific Diagram

Prevalence and Spectrum of Germline Mutations of the p53 Gene among  Patients with Sarcoma | NEJM
Prevalence and Spectrum of Germline Mutations of the p53 Gene among Patients with Sarcoma | NEJM

A Systematic p53 Mutation Library Links Differential Functional Impact to  Cancer Mutation Pattern and Evolutionary Conservation
A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation

Cancers | Free Full-Text | TP53 Mutations as a Driver of Metastasis  Signaling in Advanced Cancer Patients | HTML
Cancers | Free Full-Text | TP53 Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients | HTML

Frontiers | Genomic Analysis Revealed New Oncogenic Signatures in TP53- Mutant Hepatocellular Carcinoma
Frontiers | Genomic Analysis Revealed New Oncogenic Signatures in TP53- Mutant Hepatocellular Carcinoma

The role of TP53 gain-of-function mutation in multifocal glioblastoma |  SpringerLink
The role of TP53 gain-of-function mutation in multifocal glioblastoma | SpringerLink

Nucleotide variations of TP53 exon 4 found in intracranial meningioma and  in silico prediction of their significance
Nucleotide variations of TP53 exon 4 found in intracranial meningioma and in silico prediction of their significance

Alterations in TP53 gene – Implications in Tumorigenesis Process and  Prognosis in Central Nervous System Cancer | IntechOpen
Alterations in TP53 gene – Implications in Tumorigenesis Process and Prognosis in Central Nervous System Cancer | IntechOpen

Clinical Relevance of Gain-Of-Function Mutations of p53 in High-Grade  Serous Ovarian Carcinoma | PLOS ONE
Clinical Relevance of Gain-Of-Function Mutations of p53 in High-Grade Serous Ovarian Carcinoma | PLOS ONE

Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer  Genome Atlas - ScienceDirect
Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas - ScienceDirect

Frontiers | Mutant p53 in Cancer Progression and Targeted Therapies
Frontiers | Mutant p53 in Cancer Progression and Targeted Therapies

IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene? | HTML
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene? | HTML

50 most common somatic mutations in TP53 from IARC R18: most of the... |  Download Scientific Diagram
50 most common somatic mutations in TP53 from IARC R18: most of the... | Download Scientific Diagram

Mutant p53 as a guardian of the cancer cell | Cell Death & Differentiation
Mutant p53 as a guardian of the cancer cell | Cell Death & Differentiation